Mechanism of foam breakage by a defoamer. This inolves spreading of an water-insoluble surfactant on the bubble surfaces.
Category
Antifoam function as an effective foam suppressor. Antifoam 204 contains 100% active components and is a mixture of organic non-silicone polypropylene-based polyether dispersions. It does not contain mineral oil. Antifoam 204 can itself be considered a surfactant, but it contains no other surfactants. This product is synthetic and not derived from animal or plant sources. Antifoam 204 can be sterilized repeatedly. The flow properties of Antifoam 204 are such that it can be pumped to a fermenter on an as-needed basis. For use in microbiological media, Sigma recommends a starting concentration of between 0.005% and 0.01%.
Application
Antifoam 204 has been used:
- To suppress bubbling in thylakoid solutions during intramembrane isoprene quantification
- as a component of fed-batch continuous culture fermentation medium
- To suppress severe foaming in fermenter
Dose
Features and Benefits
- Highly versatile surfactant for your cell biology and biochemical research
- Suitable for microbiological culture
Other Notes
Contains 100% active components and is a mixture of non-silicone organic defoamers in a polyol dispersion. Can be sterilized repeatedly.
Note
Mechanism of foam breakage by a defoamer. This inolves spreading of an water-insoluble surfacatant on the bubble surfaces.
RXSOL-16-2066-025 is antifoam emulsion and its more concentrated antifoam emulsion. It has excellent candidates for controlling foam in amine and glycol dehydration units. This is suitable products for gas plants and have excellent stability in the presence of salts, resulting in reduced deposits on the plant’s equipment. RXSOL-16-2066-025 help preserve foam control under the severe conditions of a dehydrating unit. These conditions can remove water from other antifoam emulsions, rendering them immediately inactive.
MSDS
| Product Name | ANTIFOAM |
| Part Number | RXSOL-16-2066-025 |
Company Details:
RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA
Branch : Kandla, Mumbai , Chennai, Vizag, Kolkata, UAE , OMAN , CANADA and KENYA
| Phone | +91 22 20871200 - 1400 |
| Fax | +91 22 27612100 :::AOH :0091 9821214367 |
| mail@rxmarine.com | |
| Website | www.rxmraine.comA |
| Pure substance/mixture | Mixture |
| No hazardous ingredients | 0 |
GHS Classification
Not a hazardous substance or mixture.
| Precautionary Statements |
Prevention:
Wash hands thoroughly after handling.
Response:
Get medical advice/ attention if you feel unwell.
Storage:
Store in accordance with local regulations.
|
| Other hazards | None known. |
| In case of eye contact | Rinse with plenty of water. Get medical attention if symptoms occur. |
| In case of skin contact | Wash off with soap and plenty of water. Get medical attention if symptoms occur. |
| If swallowed | Rinse mouth. Get medical attention if symptoms occur. |
| If inhaled | Get medical attention if symptoms occur. |
| Protection of first-aiders | In event of emergency assess the danger before taking action. Do not put yourself at risk of injury. If in doubt, contact emergency responders. Use personal protective equipment as required. |
| Notes to physician | Treat symptomatically. |
| Most important symptoms and effects, both acute and delayed | See Section 11 for more detailed information on health effects and symptoms. |
| Suitable extinguishing media | Use extinguishing measures that are appropriate to local circumstances and the urrounding environment. |
| Unsuitable extinguishing media | None known. |
| Specific hazards during firefighting | Not flammable or combustible. |
|
Hazardous combustion products |
Decomposition products may include the following materials: Carbon oxides |
| Special protective equipment for firefighters | Use personal protective equipment. |
| Specific extinguishing methods | Fire residues and contaminated fire extinguishing water must be disposed of in accordance with local regulations. |
| Personal precautions, protective equipment and emergency procedures | Ensure clean-up is conducted by trained personnel only. Refer to protective measures listed in sections 7 and 8. |
| Environmental precautions | Do not allow contact with soil, surface or ground water. |
| Methods and materials for containment and cleaning up |
Stop leak if safe to do so. Contain spillage, and then collect with non-
combustible absorbent material, (e.g. sand, earth, diatomaceous earth,
vermiculite) and place in container for disposal according to local / national regulations (see section 13). For large spills, dike spilled material or otherwise contain material to ensure runoff does not reach a waterway. Do not flush into surface water or sanitary sewer system.
|
| Advice on protection against fire and explosion | Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge. |
| Incompatible materials | Keep away from alkalis, strong oxidizing agents and metals. Provide containment walls of adequate capacity to hold any accidental spills. |
| Hygiene measures | Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance. For precautions see section 2.2. |
| Precautions for safe handling | Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols. |
| Storage conditions | Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition. |
| Storage class | Storage class (TRGS 510): 3: Flammable liquids |
| Specific end use(s) | Apart from the uses mentioned in section 1.2 no other specific uses are stipulated |
| Advice on general occupational hygiene | Advice on safe handling Observe label precautions. Change contaminated clothing. Wash hands after working with substance. |
| Exposure controls | Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. |
| Control parameters | Ingredients with workplace control parameters Contains no substances with occupational exposure limit values. |
| Engineering Control | Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. |
| Eye/face protection | Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses |
| Body Protection | Flame retardant antistatic protective clothing. |
| Skin protection | Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it. Full contact Material: Fluorinated rubber Minimum layer thickness: 0,7 mm Break through time: 480 min Material tested:Vitoject® (KCL 890 / Aldrich Z677698, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0,4 mm Break through time: 30 min Material tested:Camatril® (KCL 730 / Aldrich Z677442, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the EC approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. |
| Respiratory protection | Required when vapours/aerosols are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system. Recommended Filter type: Filter type ABEK The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented. |
| Other Protection Measure | Handle in accordance with good industrial hygiene and safety practice. |
| Control of environmental exposure | Do not let product enter drains. Risk of explosion. |
| Physical state | Clear, liquid |
| Colour | Colorless |
| Odour | No data available |
| Odor Threshold | No data available |
| pH | No data available |
| Melting Point | 0 °C |
| Boiling Point | 136 - 140 °C at 1.013 hPa |
| Flash Point | 25 °C - closed cup |
| Evaporation Rate | Not Applicable |
| Flammability (solid, gas) | No data available |
| Explosive limits | No Data Available |
| Upper/lower flammability or explosive limits | 7 %(V) / 1,1 %(V) |
| Autoignition temperature | No data available |
| Decomposition temperature | No data available |
| Vapour pressure | 24 hPa at 37,70 °C |
| Density | 0,865 g/cm3 at 20 °C |
| Relative Density | No data available |
| Relative vapor density | 3,67 - (Air = 1.0) |
| Freezing point | No data available |
| Viscosity | No data available |
| Partition coefficient | No data available |
| Explosive properties | No data available |
| Solubility | No data available |
| Ignition temperature | No information available. |
| Particle characteristics | No data available |
| Reactivity | Vapor/air-mixtures are explosive at intense warming. |
| Stability | The product is chemically stable under standard ambient conditions (room temperature) . . |
| Possibility of hazardous reactions | No data available |
| Conditions to avoid | Heating. |
| Incompatible materials | Strong oxidizing agents |
| Hazardous decomposition products | In the event of fire: see section 5 |
| Acute toxicity | LD50 Oral - Rat - male - 3.523 mg/kg (Xylene) (EC Directive 92/69/EEC B.1 Acute Toxicity (Oral)) Remarks: (ECHA) Acute toxicity estimate Inhalation - 4 h - 12 mg/l - vapor(Calculation method) LC50 Inhalation - Rat - male - 4 h - 29,09 mg/l - vapor (Xylene) (Regulation (EC) No. 440/2008, Annex, B.2) Remarks: (Regulation (EC) No 1272/2008, Annex VI) Acute toxicity estimate Dermal - 1.376 mg/kg (Calculation method) LD50 Dermal - Rabbit - > 1.700 mg/kg (Xylene) Remarks: (RTECS) |
| Skin corrosion/irritation | Skin - Rabbit (Xylene) Result: Moderate skin irritation - 24 h Remarks: (IUCLID) Remarks: Drying-out effect resulting in rough and chapped skin. After long-term exposure to the chemical: Dermatitis |
| Serious eye damage/eye irritation | Eyes - Rabbit (Xylene) Result: Causes serious eye irritation. - 24 h Remarks: (RTECS) |
| Respiratory or skin sensitization | Local lymph node assay (LLNA) - Mouse (Xylene) Result: negative (OECD Test Guideline 429) |
| Toxic Effects on Human | May cause damage to the following organs: upper respiratory tract. Other Toxic Effects on Humans: Hazardous in case of skin contact (irritant, sensitizer), of ingestion, of inhalation (lung irritant, lung sensitizer). |
| Carcinogenicity | No data available |
| Germ cell mutagenicity | Test Type: Mutagenicity (mammal cell test): chromosome aberration. (Xylene) Test system: Chinese hamster ovary cells Metabolic activation: with and without metabolic activation Method: Regulation (EC) No. 440/2008, Annex, B.10 Result: negative Remarks: (National Toxicology Program) Test Type: Ames test (Xylene) Test system: Salmonella typhimurium Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471 Result: negative Test Type: sister chromatid exchange assay (Xylene) Test system: Chinese hamster ovary cells Metabolic activation: with and without metabolic activation Method: Regulation (EC) No. 440/2008, Annex, B.19 Result: negative (Xylene) Test Type: dominant lethal test Species: Mouse Method: OECD Test Guideline 478 Result: negative |
| Reproductive toxicity | No data available |
| Specific target organ toxicity - single exposure | No data available |
| Endocrine disrupting properties | The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. Repeated dose toxicity - Rat - male and female - Oral - 90 d - NOAEL (No observed adverse effect level) - 150 mg/kg - LOAEL (Lowest observed adverse effect level) - 150 mg/kg (Xylene) Blurred vision, Incoordination., Headache, Nausea, Vomiting, Dizziness, Weakness, anemia, Prolonged or repeated exposure to skin causes defatting and dermatitis. (Xylene) To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. (Xylene) After absorption: (Xylene) Systemic effects: (Xylene) Headache somnolence Dizziness agitation, spasms narcosis inebriation (Xylene) Effect potentiated by: ethanol (Xylene) Other dangerous properties can not be excluded. (Xylene) Handle in accordance with good industrial hygiene and safety practice. (Xylene) |
| Bioaccumulative potential | No data available |
| Persistence and degradability | No data available |
| Toxicity to fish | Static test LC50 - Oncorhynchus mykiss (rainbow trout) - 2,60 mg/l - 96 h (Xylene) (OECD Test Guideline 203) |
| Toxicity to daphnia and other aquatic invertebrates | Static test EC50 - Daphnia - 108,82 mg/l - 48 h Remarks: (ECHA) |
| Toxicity to algae | Static test EC50 - Pseudokirchneriella subcapitata - 4,36 mg/l - 73 h (Xylene) (OECD Test Guideline 201) |
| Toxicity to bacteria | Remarks: (ECHA) (Xylene) |
| Mobility in soil | No Information available |
| Results of PBT and vPvB assessment | This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. |
| Endocrine disrupting properties | The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. |
| Other adverse effects | No data available |
| Disposal methods | The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems. |
| Contaminated packaging | Dispose of as unused product. |
| Waste treatment Method | See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions. |
| UN number | ADR/RID:1307 IMDG:1307 IATA:1307 |
| UN proper shipping name | ADR/RID:Xylenes IMDG:Xylenes IATA:Xylenes |
| Transport hazard class(es) | ADR/RID:3 IMDG:3 IATA:3 |
| Packaging group | ADR/RID:III IMDG:III IATA:III |
| Environmental hazards | ADR/RID:No IMDG: No IATA: No |
| Further information | No data available |
| Inventory status | Components are on the following inventories: Polymaleic acid: - US TSCA, Canadian DSL, EU EINECS, Australian AICS, Korean, Philippine PICCS and Chinese Xi irritant R 36/38 Irritant to eyes & skin R 41 Risk of serious damage to eyes S24/25 Avoid contact with skin and eyes S26/28 In case of contact eyes & skin, rinse with plenty water and seek medical advice Section 312/313: Not listed. Not listed under California proposition 65. |
| Safety, health and environmental regulations/legislation specific for the substance or mixture | This material safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006. |
| National legislation | Seveso III Directive 2012/18/EU of the European Parliament and of the Council on the control of major-accident hazards involving dangerous substances. FLAMMABLE LIQUIDS |
| Other regulations | Observe work restrictions regarding maternity protection in accordance to Dir 92/85/EEC or stricter national regulations where applicable. Take note of Dir 94/33/EC on the protection of young people at work. |
| Chemical Safety Assessment | A Chemical Safety Assessment has been carried out for this substance. |
| Other Information |
The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and weassume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Rx Marine International has been advised of the possibility of such damages. DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable. |